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CIC Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CIC Antibody (N-term) AP10705a
    CIC Antibody (N-term) (Cat. #AP10705a) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the CIC antibody detected the CIC protein (arrow).
    detail
  • IHC-P - CIC Antibody (N-term) AP10705a
    CIC antibody (N-term) (Cat. #AP10705a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CIC antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q96RK0
Other Accession Q924A2, NP_055940.3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 163820 Da
Antigen Region 174-203 aa
Additional Information
Gene ID 23152
Other Names Protein capicua homolog, CIC, KIAA0306
Target/Specificity This CIC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the N-terminal region of human CIC.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCIC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CIC
Synonyms KIAA0306
Function Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Tissue Location Expressed in fetal brain.
Research Areas
Citations (0)
citation

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Background

Transcriptional repressor which may play a role in development of the central nervous system (CNS).

References

Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Yoshimoto, M., et al. Cancer Genet. Cytogenet. 195(1):1-11(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 365.00
$ 140.00
Cat# AP10705a
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