|Application ||WB, E|
|Other Accession||Q4KLP0, A2ATU0, NP_061176.3|
|Calculated MW||103077 Da|
|Antigen Region||392-421 aa|
|Other Names||Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, Dehydrogenase E1 and transketolase domain-containing protein 1, DHTKD1, KIAA1630|
|Target/Specificity||This DHTKD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-421 amino acids from the Central region of human DHTKD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DHTKD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
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