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ORMDL3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ORMDL3 Antibody (Center) AP10739c
    All lanes : Anti-ORMDL3 Antibody (Center) at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: mouse testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 17 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
  • CITATIONS: 3
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N138
Other Accession Q6QI25, Q9CPZ6, Q5XJR6, Q0VD15, Q9CQZ0, Q53FV1, Q5E972, Q5XH57, Q9P0S3, Q8JFB7, Q29RQ9, NP_644809.1
Reactivity Human, Mouse
Predicted Rat, Zebrafish, Xenopus, Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 17495 Da
Antigen Region 53-81 aa
Additional Information
Gene ID 94103
Other Names ORM1-like protein 3, ORMDL3
Target/Specificity This ORMDL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human ORMDL3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsORMDL3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ORMDL3
Function Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
Cellular Location Endoplasmic reticulum membrane; Multi- pass membrane protein
Tissue Location Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus
Research Areas
Citations ( 0 )

Background

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

References

Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010) Liu, X., et al. Nat. Genet. 42(8):658-660(2010) Halapi, E., et al. Eur. J. Hum. Genet. 18(8):902-908(2010) Dobbins, S.E., et al. Int. J. Cancer (2010) In press : McGovern, D.P., et al. Nat. Genet. 42(4):332-337(2010)

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$ 295.00
$ 99.00
Cat# AP10739c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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