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TMLHE Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TMLHE Antibody (N-term) AP10744a
    TMLHE Antibody (N-term) (Cat. #AP10744a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TMLHE antibody detected the TMLHE protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NVH6
Other Accession Q91ZE0, Q0VC74, NP_060666.1
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49518 Da
Antigen Region 120-149 aa
Additional Information
Gene ID 55217
Other Names Trimethyllysine dioxygenase, mitochondrial, Epsilon-trimethyllysine 2-oxoglutarate dioxygenase, Epsilon-trimethyllysine hydroxylase, TML hydroxylase, TML-alpha-ketoglutarate dioxygenase, TML dioxygenase, TMLD, TMLHE, TMLH
Target/Specificity This TMLHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the N-terminal region of human TMLHE.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMLHE Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TMLH
Function Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Cellular Location Mitochondrion matrix
Tissue Location All isoforms, but isoform 8, are widely expressed in adult and fetal tissues. Isoform 8 is restricted to heart and skeletal muscle.
Research Areas
Citations (0)

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This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.


Monfregola, J., et al. Gene 395 (1-2), 86-97 (2007) :
Monfregola, J., et al. J. Cell. Physiol. 204(3):839-847(2005)
Vaz, F.M., et al. J. Biol. Chem. 276(36):33512-33517(2001)
Rogner, U.C., et al. Genome Res. 6(10):922-934(1996)

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Cat# AP10744a
(40 western blots)
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