|Application ||WB, IHC-P, E|
|Calculated MW||37764 Da|
|Antigen Region||247-276 aa|
|Other Names||Complex I intermediate-associated protein 30, mitochondrial, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1, NDUFAF1, CIA30|
|Target/Specificity||This NDUFAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human NDUFAF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NDUFAF1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|
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Provided below are standard protocols that you may find useful for product applications.
The NDUFAF1 gene encodes the human homolog of a Neurospora crassa Cia30 protein involved in the assembly of complex I.
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Dunning, C.J., et al. EMBO J. 26(13):3227-3237(2007)
Vogel, R.O., et al. Mol. Genet. Metab. 91(2):176-182(2007)
Vogel, R.O., et al. Genes Dev. 21(5):615-624(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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