|Application ||WB, IHC-P, E|
|Other Accession||A4IFC9, NP_059128.2|
|Calculated MW||46869 Da|
|Antigen Region||25-52 aa|
|Other Names||Prostate tumor-overexpressed gene 1 protein, PTOV-1, Activator interaction domain-containing protein 2, PTOV1, ACID2|
|Target/Specificity||This PTOV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human PTOV1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PTOV1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.|
|Cellular Location||Cell membrane. Cytoplasm, perinuclear region. Nucleus. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts|
|Tissue Location||Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
Morote, J., et al. Clin. Cancer Res. 14(9):2617-2622(2008)
Santamaria, A., et al. Mol. Cell. Biol. 25(5):1900-1911(2005)
Mittler, G., et al. EMBO J. 22(24):6494-6504(2003)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Santamaria, A., et al. Am. J. Pathol. 162(3):897-905(2003)
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