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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CORO7 Antibody (N-term)   

CORO7 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CORO7 Antibody (N-term) AP10766a
    CORO7 Antibody (N-term) (Cat. #AP10766a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CORO7 antibody detected the CORO7 protein (arrow).
  • IHC-P - CORO7 Antibody (N-term) AP10766a
    CORO7 antibody (N-term) (Cat. #AP10766a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CORO7 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P57737
Other Accession NP_078811.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 100605 Da
Antigen Region 173-202 aa
Additional Information
Gene ID 79585
Other Names Coronin-7, Crn7, 70 kDa WD repeat tumor rejection antigen homolog, CORO7
Target/Specificity This CORO7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the N-terminal region of human CORO7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCORO7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CORO7
Function F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post- Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
Cellular Location Golgi apparatus membrane. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Cytoplasm, cytosol. Note=Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments
Tissue Location Widely expressed. Expressed in the spleen, peripheral leukocytes, testes, brain, thymus and small intestine
Research Areas
Citations (0)

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Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 [PubMed 15327992] [PubMed 16905771]).


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Rybakin, V., et al. Cell. Mol. Life Sci. 65(15):2419-2430(2008)
Rybakin, V., et al. J. Biol. Chem. 281(41):31070-31078(2006)
Rybakin, V., et al. FEBS Lett. 573 (1-3), 161-167 (2004) :

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$ 295.00
$ 99.00
Cat# AP10766a
(40 western blots)
Availability: In Stock
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