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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GNMT Antibody (C-term)   

GNMT Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GNMT Antibody (C-term) AP1076b
    Anti-GNMT Antibody (C-term) at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - GNMT Antibody (C-term) AP1076b
    Western blot analysis of anti-GNMT Pab (Cat. #AP1076b) in CEM cell line tissue lysate (35ug/lane).GNMT(arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14749
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32742 Da
Antigen Region 218-248 aa
Additional Information
Gene ID 27232
Other Names Glycine N-methyltransferase, GNMT
Target/Specificity This GNMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the C-terminal region of human GNMT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNMT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Cellular Location Cytoplasm.
Tissue Location Abundant in liver.
Research Areas
Citations ( 0 )


Glycine N-methyltransferase catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. GNMT acts as an enzyme to regulate the ratio of S-adenosylmethionine to S-adenosylhomocysteine (AdoHcy) and participates in the detoxification pathway in liver cells.


Augoustides-Savvopoulou, P., et al., J. Inherit. Metab. Dis. 26(8):745-759 (2003). Tseng, T.L., et al., Cancer Res. 63(3):647-654 (2003). Luka, Z., et al., Hum. Genet. 110(1):68-74 (2002). Strausberg RL, et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Mudd, S.H., et al., J. Inherit. Metab. Dis. 24(4):448-464 (2001).

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$ 295.00
$ 99.00
Cat# AP1076b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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