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AL2SA Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q53TS8 |
| Other Accession | NP_689738.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 209056 Da |
| Antigen Region | 152-181 aa |
| Gene ID | 151254 |
|---|---|
| Other Names | Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein, ALS2CR11 |
| Target/Specificity | This AL2SA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-181 amino acids from the N-terminal region of human AL2SA. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AL2SA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | C2CD6 (HGNC:14438) |
|---|---|
| Function | Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains. Targets the preassembled CatSper complexes to elongating flagella, where it links the channel- carrying vesicles and motor proteins. |
| Cellular Location | Cell projection, cilium, flagellum membrane {ECO:0000250|UniProtKB:E9Q9F6}. Note=Specifically located in the principal piece of sperm tail. {ECO:0000250|UniProtKB:E9Q9F6} |
| Tissue Location | Expressed in testis (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Jia, L., et al. Genomics 79(1):7-17(2002)
Hadano, S., et al. Nat. Genet. 29(2):166-173(2001)
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