|Application ||WB, E|
|Other Accession||Q64HY3, P0CG40, Q6NW96, Q5XGT8, Q8BMJ8, Q6P0J3, Q64HY5, Q9JHX2, Q6BEB4, NP_874359.2|
|Predicted||Chicken, Zebrafish, Xenopus|
|Calculated MW||48674 Da|
|Antigen Region||386-415 aa|
|Other Names||Transcription factor Sp8, Specificity protein 8, SP8|
|Target/Specificity||This SP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SP8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SP8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
Lee, M.T., et al. Mol. Psychiatry (2010) In press :
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Milona, M.A., et al. BMC Genomics 5 (1), 86 (2004) :
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