|Application ||WB, IHC-P, FC, E|
|Calculated MW||118834 Da|
|Antigen Region||393-421 aa|
|Other Names||Acyl-CoA dehydrogenase family member 10, ACAD-10, 1399-, ACAD10|
|Target/Specificity||This ACD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-421 amino acids from the Central region of human ACD10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACD10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA.|
|Tissue Location||Widely expressed with highest expression in fetal brain, followed by heart, muscle, kidney and adult brain Expression levels varying from isoform to isoform|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Bian, L., et al. Diabetologia 53(7):1349-1353(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
Ye, X., et al. Mol. Biol. Rep. 31(3):191-195(2004)
Sogayar, M.C., et al. Genome Res. 14(7):1413-1423(2004)
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