TIFAB Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q6ZNK6 |
Other Accession | NP_001092691.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 17888 Da |
Antigen Region | 37-66 aa |
Gene ID | 497189 |
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Other Names | TRAF-interacting protein with FHA domain-containing protein B, TIFA-like protein, TIFAB {ECO:0000303|PubMed:15047173} |
Target/Specificity | This TIFAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human TIFAB. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TIFAB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TIFAB {ECO:0000303|PubMed:15047173} |
---|---|
Function | Inhibits TIFA-mediated TRAF6 activation possibly by inducing a conformational change in TIFA. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TIFAB associates with TIFA (MIM 609028) and inhibits TIFA-mediated activation of NF-kappa-B (NFKB1; MIM 164011) (Matsumura et al., 2004 [PubMed 15047173]).
References
Matsumura, T., et al. Biochem. Biophys. Res. Commun. 317(1):230-234(2004)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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