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>   home   >   Products   >   Primary Antibodies   >   RM51 Antibody (C-term)   

RM51 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RM51 Antibody (C-term) AP10931b
    RM51 Antibody (C-term) (Cat. #AP10931b) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the RM51 antibody detected the RM51 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q4U2R6
Other Accession NP_057581.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 100-128 aa
Additional Information
Other Names 39S ribosomal protein L51, mitochondrial, L51mt, MRP-L51, bMRP-64, bMRP64, MRPL51, MRP64
Target/Specificity This RM51 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the C-terminal region of human RM51.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRM51 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRPL51
Synonyms MRP64
Cellular Location Mitochondrion EMBL; AB049959; BAB41012.1; -; mRNA EMBL; AF212248; AAK14931.1; -; mRNA EMBL; AF151075; AAF36161.1; -; mRNA EMBL; BC000191; AAH00191.1; -; mRNA EMBL; BC014329; AAH14329.1; -; mRNA EMBL; AB051355; BAB54944.1; -; Genomic_DNA CCDS; CCDS8547.1; - RefSeq; NP_057581.2; NM_016497.3 UniGene; Hs.55847; - PDB; 3J7Y; EM; 3.40 A; i=1-128 PDB; 3J9M; EM; 3.50 A; i=1-128 PDBsum; 3J7Y; - PDBsum; 3J9M; - ProteinModelPortal; Q4U2R6; - SMR; Q4U2R6; - BioGrid; 119414; 31 IntAct; Q4U2R6; 4 MINT; MINT-6775055; - STRING; 9606.ENSP00000229238; - BioMuta; MRPL51; - DMDM; 74762954; - EPD; Q4U2R6; - MaxQB; Q4U2R6; - PaxDb; Q4U2R6; - PeptideAtlas; Q4U2R6; - PRIDE; Q4U2R6; - TopDownProteomics; Q4U2R6; - Ensembl; ENST00000229238; ENSP00000229238; ENSG00000111639 GeneID; 51258; - KEGG; hsa:51258; - UCSC; uc001qom.3; human CTD; 51258; - GeneCards; MRPL51; - HGNC; HGNC:14044; MRPL51 HPA; HPA039923; - MIM; 611855; gene neXtProt; NX_Q4U2R6; - OpenTargets; ENSG00000111639; - PharmGKB; PA30984; - eggNOG; KOG4045; Eukaryota eggNOG; ENOG4111M24; LUCA GeneTree; ENSGT00390000018821; - HOGENOM; HOG000154145; - HOVERGEN; HBG093901; - InParanoid; Q4U2R6; - KO; K17432; - OMA; FNRHGKY; - OrthoDB; EOG091G0V79; - PhylomeDB; Q4U2R6; - TreeFam; TF106130; - Reactome; R-HSA-5368286; Mitochondrial translation initiation Reactome; R-HSA-5389840; Mitochondrial translation elongation Reactome; R-HSA-5419276; Mitochondrial translation termination ChiTaRS; MRPL51; human GenomeRNAi; 51258; - PRO; PR:Q4U2R6; - Proteomes; UP000005640; Chromosome 12 Bgee; ENSG00000111639; - CleanEx; HS_MRPL51; - ExpressionAtlas; Q4U2R6; baseline and differential Genevisible; Q4U2R6; HS GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome GO; GO:0005762; C:mitochondrial large ribosomal subunit; IDA:UniProtKB GO; GO:0005761; C:mitochondrial ribosome; IDA:UniProtKB GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB GO; GO:0032543; P:mitochondrial translation; ISS:UniProtKB GO; GO:0070125; P:mitochondrial translational elongation; TAS:Reactome GO; GO:0070126; P:mitochondrial translational termination; TAS:Reactome GO; GO:0006412; P:translation; ISS:UniProtKB InterPro; IPR019373; Ribosomal_L51_mit Pfam; PF10244; MRP-L51; 1 1: Evidence at protein level; 3D-structure; Complete proteome; Mitochondrion; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide TRANSIT 1 31 Mitochondrion. CHAIN 32 128 39S ribosomal protein L51, mitochondrial /FTId=PRO_0000273082 VARIANT 102 102 M -> I (in dbSNP:rs9526) /FTId=VAR_030079 CONFLICT 79 79 W -> R (in Ref. 3; AAF36161) SEQUENCE 128 AA; 15095 MW; 9DB4720D5B387A5D CRC64; MAGNLLSGAG RRLWDWVPLA CRSFSLGVPR LIGIRLTLPP PKVVDRWNEK RAMFGVYDNI GILGNFEKHP KELIRGPIWL RGWKGNELQR CIRKRKMVGS RMFADDLHNL NKRIRYLYKH FNRHGKFR
Citations (0)

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Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q.

References

Zhang, Z., et al. Genomics 81(5):468-480(2003)
Koc, E.C., et al. J. Biol. Chem. 276(47):43958-43969(2001)
Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :
Suzuki, T., et al. J. Biol. Chem. 276(35):33181-33195(2001)

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$ 295.00
$ 99.00
Cat# AP10931b
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(40 western blots)
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