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DEFB1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DEFB1 Antibody (N-term) AP10958a
    DEFB1 Antibody (N-term) (Cat. #AP10958a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the DEFB1 antibody detected the DEFB1 protein (arrow).
  • IHC-P - DEFB1 Antibody (N-term) AP10958a
    DEFB1 antibody (N-term) (Cat. #AP10958a) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DEFB1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - DEFB1 Antibody (N-term) AP10958a
    Confocal immunofluorescent analysis of DEFB1 Antibody (N-term)(Cat#AP10958a) with MDA-MB231 cell followed by Alexa Fluor搴?488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
  • FC - DEFB1 Antibody (N-term) AP10958a
    DEFB1 Antibody (N-term) (Cat. #AP10958a) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P60022
Other Accession P61261, NP_005209.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 7420 Da
Antigen Region 11-36 aa
Additional Information
Gene ID 1672
Other Names Beta-defensin 1, BD-1, hBD-1, Defensin, beta 1, DEFB1, BD1, HBD1
Target/Specificity This DEFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-36 amino acids from the N-terminal region of human DEFB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDEFB1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DEFB1
Synonyms BD1, HBD1
Function Has bactericidal activity.
Cellular Location Secreted.
Tissue Location Plasma.
Research Areas
Citations (0)

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Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.


Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Garreis, F., et al. Histochem. Cell Biol. 134(1):59-73(2010) Segat, L., et al. Int. J. Dermatol. 49(6):653-657(2010) Tiszlavicz, Z., et al. Pancreatology 10(4):483-490(2010) Yin, L., et al. BMC Immunol. 11, 37 (2010) :

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Cat# AP10958a
(40 western blots)
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