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ASCL2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ASCL2 Antibody (N-term) AP10976A
    ASCL2 Antibody (N-term) (Cat. #AP10976a) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ASCL2 antibody detected the ASCL2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99929
Other Accession Q90259, P19360, O35885, Q2EGB9, Q06234, P19359, Q02067, P50553, NP_005161.1
Reactivity Human, Mouse
Predicted Rat, Xenopus, Bovine, Zebrafish
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20185 Da
Antigen Region 38-65 aa
Additional Information
Gene ID 430
Other Names Achaete-scute homolog 2, ASH-2, hASH2, Class A basic helix-loop-helix protein 45, bHLHa45, Mash2, ASCL2, BHLHA45, HASH2
Target/Specificity This ASCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human ASCL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsASCL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASCL2
Synonyms BHLHA45, HASH2
Function AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:11440538}
Tissue Location Expressed specifically in the extravillous trophoblasts of the developing placenta
Research Areas
Citations (0)

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This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.


Stange, D.E., et al. Gut 59(9):1236-1244(2010)
Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)
Shahib, M.N., et al. J Reprod Med 51(11):892-896(2006)
Jubb, A.M., et al. Oncogene 25(24):3445-3457(2006)

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Cat# AP10976A
(40 western blots)
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