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WIPF2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - WIPF2 Antibody (C-term) AP10977b
    WIPF2 Antibody (C-term) (Cat. #AP10977b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the WIPF2 antibody detected the WIPF2 protein (arrow).
  • IHC-P - WIPF2 Antibody (C-term) AP10977b
    WIPF2 antibody (C-term) (Cat. #AP10977b) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the WIPF2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TF74
Other Accession NP_573571.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46289 Da
Antigen Region 392-419 aa
Additional Information
Gene ID 147179
Other Names WAS/WASL-interacting protein family member 2, WASP-interacting protein-related protein, WIP- and CR16-homologous protein, WIP-related protein, WIPF2, WICH, WIRE
Target/Specificity This WIPF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-419 amino acids from the C-terminal region of human WIPF2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWIPF2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WIPF2
Synonyms WICH, WIRE
Function Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.
Cellular Location Cytoplasm, cytoskeleton Note=Localized to stress fibers and bundles of actin filaments
Tissue Location Expressed mainly in brain, colon, lung and stomach (at protein level). Ubiquitously expressed, with high expression in brain, kidney, lung, and placenta
Research Areas
Citations (0)

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This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery.


Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Salazar, M.A., et al. J. Biol. Chem. 278(49):49031-49043(2003)
Aspenstrom, P. Exp. Cell Res. 279(1):21-33(2002)
Kato, M., et al. Biochem. Biophys. Res. Commun. 291(1):41-47(2002)

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$ 295.00
$ 99.00
Cat# AP10977b
(40 western blots)
Availability: In Stock
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