NDUF3 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q9BU61 |
Other Accession | NP_951032.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 20350 Da |
Antigen Region | 12-40 aa |
Gene ID | 25915 |
---|---|
Other Names | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3, NDUFAF3, C3orf60 |
Target/Specificity | This NDUF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human NDUF3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NDUF3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NDUFAF3 |
---|---|
Synonyms | C3orf60 |
Function | Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). |
Cellular Location | Nucleus. Mitochondrion inner membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified.
References
Saada, A., et al. Am. J. Hum. Genet. 84(6):718-727(2009)
Hammami-Hamza, S., et al. Int. J. Dev. Biol. 47(1):71-76(2003)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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