|Application ||WB, IHC-P, E|
|Calculated MW||20350 Da|
|Antigen Region||12-40 aa|
|Other Names||NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3, NDUFAF3, C3orf60|
|Target/Specificity||This NDUF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human NDUF3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NDUF3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|
|Cellular Location||Nucleus. Mitochondrion inner membrane|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified.
Saada, A., et al. Am. J. Hum. Genet. 84(6):718-727(2009)
Hammami-Hamza, S., et al. Int. J. Dev. Biol. 47(1):71-76(2003)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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