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GDPD5 Antibody (center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8WTR4 |
| Other Accession | NP_110419.5 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 68586 Da |
| Antigen Region | 342-369 aa |
| Gene ID | 81544 |
|---|---|
| Other Names | Glycerophosphodiester phosphodiesterase domain-containing protein 5, 31--, Glycerophosphodiester phosphodiesterase 2, GDPD5, GDE2 |
| Target/Specificity | This GDPD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-369 amino acids from the Central region of human GDPD5. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GDPD5 Antibody (center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GDPD5 (HGNC:28804) |
|---|---|
| Function | Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation (By similarity). Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (By similarity). May contribute to the osmotic regulation of cellular glycerophosphocholine (By similarity). |
| Cellular Location | Endomembrane system {ECO:0000250|UniProtKB:Q640M6}; Multi-pass membrane protein. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q640M6}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q640M6}. Note=In a punctate perinuclear pattern {ECO:0000250|UniProtKB:Q640M6} |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).
References
Lang, Q., et al. Mol. Biol. Rep. 35(3):351-359(2008) Rao, M., et al. Science 309(5744):2212-2215(2005) Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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$ 365.00
$ 140.00
Cat# AP10992c
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