- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||68586 Da|
|Antigen Region||342-369 aa|
|Other Names||Glycerophosphodiester phosphodiesterase domain-containing protein 5, 31--, Glycerophosphodiester phosphodiesterase 2, GDPD5, GDE2|
|Target/Specificity||This GDPD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-369 amino acids from the Central region of human GDPD5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GDPD5 Antibody (center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.|
|Cellular Location||Endomembrane system; Multi- pass membrane protein. Cytoplasm, perinuclear region. Cell projection, growth cone. Note=In a punctate perinuclear pattern.|
Provided below are standard protocols that you may find useful for product applications.
Glycerophosphodiester phosphodiesterases (GDPDs; EC 22.214.171.124), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).
Lang, Q., et al. Mol. Biol. Rep. 35(3):351-359(2008) Rao, M., et al. Science 309(5744):2212-2215(2005) Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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