|Application ||WB, IHC-P, E|
|Other Accession||NP_001137250.1, NP_060177.2|
|Calculated MW||99155 Da|
|Antigen Region||26-54 aa|
|Other Names||Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1, ASAP3, DDEFL1, UPLC1|
|Target/Specificity||This ASAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human ASAP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ASAP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes cell proliferation.|
|Tissue Location||Highly expressed in primary hepatocarcinoma. Detected in lung, liver and blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.
Ismail, S.A., et al. Cell 141(5):812-821(2010)
Ha, V.L., et al. J. Biol. Chem. 283(22):14915-14926(2008)
Fang, Z., et al. Mol. Cell Proteomics 5(8):1437-1449(2006)
Okabe, H., et al. Int. J. Oncol. 24(1):43-48(2004)
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