FBXO24 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | O75426 |
Other Accession | Q9D417, Q4R327, NP_001156971.1, NP_277041.1, NP_036304.2 |
Reactivity | Human, Mouse |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 64889 Da |
Antigen Region | 118-145 aa |
Gene ID | 26261 |
---|---|
Other Names | F-box only protein 24, FBXO24, FBX24 |
Target/Specificity | This FBXO24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human FBXO24. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FBXO24 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FBXO24 |
---|---|
Synonyms | FBX24 |
Function | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
References
Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
Cenciarelli, C., et al. Curr. Biol. 9(20):1177-1179(1999)
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