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C20orf7 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | ||||
| AP11014b | DISCONTINED INQUIRE CLICK INQUIRE Add to cart | |||
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
C20orf7 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | Q5TEU4 |
| Other Accession | NP_077025.2, NP_001034464.1 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 38918 Da |
C20orf7 Antibody (C-term) - Additional info | |
| Gene ID 79133 | |
| Other Names NDUFAF5; C20orf7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5; Probable methyltransferase C20orf7, mitochondrial | |
| Target/Specificity This C20orf7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-323 amino acids from the C-terminal region of human C20orf7. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions C20orf7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
C20orf7 Antibody (C-term) - Protein Information | |
| Name NDUFAF5 | |
| Synonyms C20orf7 | |
| Function Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. May have methyltransferase activity | |
| Cellular Location Mitochondrion inner membrane. Note=Peripherally localized on the matrix face of the mitochondrial inner membrane | |
C20orf7 Antibody (C-term) - Related products
C20orf7 Antibody (C-term) - Application data
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C20orf7 Antibody (C-term) (Cat. #AP11014b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the C20orf7 antibody detected the C20orf7 protein (arrow).
C20orf7 Antibody (C-term) - Research Areas
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BACKGROUND
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes a mitochondrial protein that is associated with the matrix face of the mitochondrial inner membrane and is required for complex I assembly. A mutation in this gene results in mitochondrial complex I deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
REFERENCES
Gerards, M., et al. J. Med. Genet. 47(8):507-512(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Sugiana, C., et al. Am. J. Hum. Genet. 83(4):468-478(2008) Lamesch, P., et al. Genomics 89(3):307-315(2007) Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
