|Application ||WB, E|
|Other Accession||Q6INE2, Q66JA9, Q8C4B4, Q90Z08, NP_001074002.1|
|Calculated MW||28137 Da|
|Antigen Region||207-236 aa|
|Other Names||Protein unc-119 homolog B, UNC119B|
|Target/Specificity||This U119B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the C-terminal region of human U119B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||U119B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N- terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells.|
|Cellular Location||Cell projection, cilium. Note=Enriched at the transition zone and extended into the proximal end of the cilium|
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Provided below are standard protocols that you may find useful for product applications.
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Scherer, S.E., et al. Nature 440(7082):346-351(2006)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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