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U119B Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A6NIH7 |
| Other Accession | Q6INE2, Q66JA9, Q8C4B4, Q90Z08, NP_001074002.1 |
| Reactivity | Human, Mouse |
| Predicted | Zebrafish, Xenopus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 28137 Da |
| Antigen Region | 207-236 aa |
| Gene ID | 84747 |
|---|---|
| Other Names | Protein unc-119 homolog B, UNC119B |
| Target/Specificity | This U119B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the C-terminal region of human U119B. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | U119B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UNC119B |
|---|---|
| Function | Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells. |
| Cellular Location | Cell projection, cilium. Note=Enriched at the transition zone and extended into the proximal end of the cilium |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Scherer, S.E., et al. Nature 440(7082):346-351(2006)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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