|Application ||WB, IHC-P, E|
|Other Accession||Q6IP02, Q6AYA0, A4IFK7, NP_659495.1|
|Predicted||Bovine, Rat, Xenopus|
|Calculated MW||23986 Da|
|Antigen Region||120-149 aa|
|Other Names||RILP-like protein 2, Rab-interacting lysosomal protein-like 2, p40phox-binding protein, RILPL2, RLP2|
|Target/Specificity||This RILPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the Central region of human RILPL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RILPL2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines. Plays a role in cellular protein transport, including protein transport away from primary cilia. May function via activation of RAC1 and PAK1 (By similarity).|
|Cellular Location||Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium|
|Tissue Location||Widely expressed. Expressed at higher level in lung.|
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Does not regulate lysosomal morphology and distribution.
Wang, T., et al. Mol. Biol. Cell 15(2):815-826(2004)
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