|Application ||WB, FC, E|
|Calculated MW||42637 Da|
|Antigen Region||297-325 aa|
|Other Names||Guanine nucleotide exchange factor for Rab-3A, Rab-3A-interacting-like protein 1, Rab3A-interacting-like protein 1, Rabin3-like 1, RAB3IL1|
|Target/Specificity||This RAB3IL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human RAB3IL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB3IL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B.|
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Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis (By similarity).
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Luo, H.R., et al. Neuron 31(3):439-451(2001)
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