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CCDC39 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CCDC39 Antibody (C-term) AP11039b
    CCDC39 Antibody (C-term) (Cat. #AP11039b) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the CCDC39 antibody detected the CCDC39 protein (arrow).
    detail
  • WB - CCDC39 Antibody (C-term) AP11039b
    CCDC39 Antibody (C-term) (Cat. #AP11039b) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CCDC39 antibody detected the CCDC39 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UFE4
Other Accession NP_852091.1
Reactivity Human, Hamster, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 109901 Da
Antigen Region 770-798 aa
Additional Information
Gene ID 339829
Other Names Coiled-coil domain-containing protein 39, CCDC39
Target/Specificity This CCDC39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 770-798 amino acids from the C-terminal region of human CCDC39.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCDC39 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC39 (HGNC:25244)
Function Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella (PubMed:21131972). Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly (PubMed:21131972).
Cellular Location Cytoplasm, cytoskeleton, cilium axoneme. Note=CCDC40 is required for localization to axonemes.
Tissue Location Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.
Research Areas
Citations (0)
citation

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References

Rose, J. Phd, et al. Mol. Med. (2010) In press :
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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$ 365.00
$ 140.00
Cat# AP11039b
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