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ICAM2 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP11047c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP11047c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ICAM2 Antibody (Center) - Product info | |
| Application | WB, FC
|
| Primary Accession | P13598 |
| Other Accession | NP_000864.2, NP_001093256.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 30654 Da |
ICAM2 Antibody (Center) - Additional info | |
| Gene ID 3384 | |
| Other Names ICAM2; Intercellular adhesion molecule 2; CD_antigen=CD102; Flags: Precursor | |
| Target/Specificity This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ICAM2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ICAM2 Antibody (Center) - Protein Information | |
| Name ICAM2 | |
| Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance | |
| Cellular Location Membrane; Single-pass type I membrane protein | |
ICAM2 Antibody (Center) - Related products
ICAM2 Antibody (Center) - Application data
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ICAM2 Antibody (Center) (Cat. #AP11047c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ICAM2 antibody detected the ICAM2 protein (arrow).
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ICAM2 Antibody (Center) (Cat. #AP11047c) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ICAM2 Antibody (Center) - Research Areas
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BACKGROUND
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
REFERENCES
Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Sato, H., et al. Biochim. Biophys. Acta 1790(10):1198-1205(2009) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)
