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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BCDO2 Antibody (N-term)   

BCDO2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BCDO2 Antibody  (N-term) AP11050a
    BCDO2 Antibody (N-term) (Cat. #AP11050a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the BCDO2 antibody detected the BCDO2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BYV7
Other Accession Q8HXG8, NP_001032367.1, NP_114144.3
Reactivity Human, Mouse
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 65674 Da
Antigen Region 71-100 aa
Additional Information
Gene ID 83875
Other Names Beta, beta-carotene 9', 10'-oxygenase, B-diox-II, Beta-carotene dioxygenase 2, BCO2, BCDO2
Target/Specificity This BCDO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human BCDO2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBCDO2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCO2
Synonyms BCDO2
Function Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in retinal pigment epithelium. Also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level).
Research Areas
Citations (0)

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BCDO2 catalyzes the asymmetric oxidative cleavage of beta-carotene in carotene metabolism (Kiefer et al., 2001 [PubMed 11278918]).


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
He, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(4):885-890(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)

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$ 295.00
$ 99.00
Cat# AP11050a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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