|Application ||WB, E|
|Calculated MW||14378 Da|
|Antigen Region||55-83 aa|
|Other Names||Interferon-induced transmembrane protein 5, Bone-restricted interferon-induced transmembrane protein-like protein, BRIL, Dispanin subfamily A member 1, DSPA1, IFITM5|
|Target/Specificity||This IFITM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human IFITM5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IFITM5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for normal bone mineralization.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (at protein level) (PubMed:24519609). Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (PubMed:24519609)|
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Provided below are standard protocols that you may find useful for product applications.
Plays a role in bone mineralization (By similarity).
Moffatt, P., et al. J. Bone Miner. Res. 23(9):1497-1508(2008) Lange, U.C., et al. BMC Dev. Biol. 3, 1 (2003) : Baird, J.W., et al. J. Biol. Chem. 276(12):9189-9198(2001)
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