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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CLEC2A Antibody (Center)   

CLEC2A Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLEC2A Antibody (Center) AP11060c
    CLEC2A Antibody (Center) (Cat. #AP11060c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CLEC2A antibody detected the CLEC2A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6UVW9
Other Accession NP_001124183.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 19972 Da
Antigen Region 79-107 aa
Additional Information
Gene ID 387836
Other Names C-type lectin domain family 2 member A, Keratinocyte-associated C-type lectin, KACL, Proliferation-induced lymphocyte-associated receptor, PILAR, CLEC2A, KACL
Target/Specificity This CLEC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CLEC2A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLEC2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KACL
Function Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti- apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Mainly expressed in skin. Also expressed in keratinocytes, spleen, thymus, small intestine, peripheral blood monocytes, bone marrow, ovary, testis and skin. High expression in CD8(+), B-lymphocytes and naive CD4(+) T-cells. Restricted mostly to proliferating lymphocytes. Not detected in myeloid leukocytes or natural killer (NK) cells.
Research Areas
Citations (0)

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CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).


Spreu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(11):5100-5105(2010)
Ozaki, Y., et al. J. Thromb. Haemost. 7 SUPPL 1, 191-194 (2009) :
Huarte, E., et al. Blood 112(4):1259-1268(2008)
Spreu, J., et al. Immunogenetics 59(12):903-912(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 295.00
$ 99.00
Cat# AP11060c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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