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SULT1C3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6IMI6 |
| Other Accession | NP_001008743.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35889 Da |
| Antigen Region | 264-292 aa |
| Gene ID | 442038 |
|---|---|
| Other Names | Sulfotransferase 1C3, ST1C3, SULT1C3 |
| Target/Specificity | This SULT1C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human SULT1C3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SULT1C3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SULT1C3 |
|---|---|
| Function | [Isoform 1]: Sulfotransferase that utilizes 3'-phospho-5'- adenylyl sulfate (PAPS) as sulfonate donor. Has sulfotransferase activity towards various substrates, such as bile acids, thyroid hormones and toward xenobiotic compounds such as chloro phenols and hydroxypyrenes. Lithocholic acid appears to be the best substrate among the endogenous compounds tested and 3,3',5,5'-tetrachloro-4,4'- biphenyldiol shows the highest specific activity among the xenobiotic compounds. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q80VR3}. |
| Tissue Location | [Isoform 1]: Not detectable in any of the tissues tested. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Has low sulphotransferase activity towards various substrates with alcohol groups (in vitro). May catalyze the sulfate conjugation of xenobiotic compounds and endogenous substrates.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Meinl, W., et al. Food Chem. Toxicol. 46(4):1249-1256(2008)
Allali-Hassani, A., et al. PLoS Biol. 5 (5), E97 (2007) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Freimuth, R.R., et al. Pharmacogenomics J. 4(1):54-65(2004)
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