|Application ||WB, FC, E|
|Other Accession||B9EHT4, NP_056341.1|
|Calculated MW||59560 Da|
|Antigen Region||368-396 aa|
|Other Names||CAP-Gly domain-containing linker protein 3, Cytoplasmic linker protein 170-related 59 kDa protein, CLIP-170-related 59 kDa protein, CLIPR-59, CLIP3, CLIPR59|
|Target/Specificity||This CLIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-396 amino acids from the C-terminal region of human CLIP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CLIP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes.|
|Cellular Location||Cell membrane; Lipid-anchor. Cytoplasm. Golgi apparatus, Golgi stack. Note=Localized to Golgi stacks as well as on tubulovesicular elements juxtaposed to Golgi cisternae|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics.
Sorice, M., et al. PLoS ONE 5 (1), E8567 (2010) :
Ding, J., et al. Mol. Cell. Biol. 29(6):1459-1471(2009)
Lallemand-Breitenbach, V., et al. J. Biol. Chem. 279(39):41168-41178(2004)
Perez, F., et al. J. Cell Biol. 156(4):631-642(2002)
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