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CLEC11A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q9Y240 |
| Other Accession | NP_002966.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35695 Da |
| Antigen Region | 145-174 aa |
| Gene ID | 6320 |
|---|---|
| Other Names | C-type lectin domain family 11 member A, C-type lectin superfamily member 3, Lymphocyte secreted C-type lectin, Stem cell growth factor, p47, CLEC11A, CLECSF3, LSLCL, SCGF |
| Target/Specificity | This CLEC11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CLEC11A. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CLEC11A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CLEC11A |
|---|---|
| Synonyms | CLECSF3, LSLCL, SCGF |
| Function | Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts (PubMed:27976999). Important for repair and maintenance of adult bone (By similarity). |
| Cellular Location | Cytoplasm. Secreted |
| Tissue Location | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver |
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.
References
Ouma, C., et al. Infect. Immun. 78(1):453-460(2010)
Keller, C.C., et al. Infect. Immun. 77(9):3864-3871(2009)
Lan, C.C., et al. Br. J. Dermatol. 160(6):1180-1187(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hollenbeck, S.T., et al. J. Surg. Res. 120(2):288-294(2004)
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