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AASS Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP11094b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP11094b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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AASS Antibody (C-term) - Product info | |
| Application | WB, FC
|
| Primary Accession | Q9UDR5 |
| Other Accession | NP_005754.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 102132 Da |
AASS Antibody (C-term) - Additional info | |
| Gene ID 10157 | |
| Other Names AASS; Alpha-aminoadipic semialdehyde synthase, mitochondrial; LKR/SDH; Lysine ketoglutarate reductase; Saccharopine dehydrogenase | |
| Target/Specificity This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 812-841 amino acids from the C-terminal region of human AASS. | |
| Dilution WB~~1:50~100WB~~1:1000 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AASS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AASS Antibody (C-term) - Protein Information | |
| Name AASS | |
| Function Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | |
| Cellular Location Mitochondrion (By similarity). | |
| Tissue Location Expressed in all 16 tissues examined with highest expression in the liver | |
AASS Antibody (C-term) - Related products
AP11094b: AASS Antibody (C-term)
AASS Antibody (C-term) - Application data
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AASS Antibody (C-term) (Cat. #AP11094b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AASS antibody detected the AASS protein (arrow).
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AASS Antibody (C-term) (Cat. #AP11094b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
AASS Antibody (C-term) - Research Areas
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BACKGROUND
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
REFERENCES
Sacksteder, K.A., et al. Am. J. Hum. Genet. 66(6):1736-1743(2000) Papes, F., et al. Biochem. J. 344 PT 2, 555-563 (1999) :
