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ACAT1 Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP11099a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP11099a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ACAT1 Antibody (N-term) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | P24752 |
| Other Accession | Q8HXY6, NP_000010.1 |
| Reactivity | Human |
| Predicted | Monkey |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 45200 Da |
ACAT1 Antibody (N-term) - Additional info | |
| Gene ID 38 | |
| Other Names ACAT1; ACAT; MAT; Acetyl-CoA acetyltransferase, mitochondrial; Acetoacetyl-CoA thiolase; T2 | |
| Target/Specificity This ACAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human ACAT1. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACAT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACAT1 Antibody (N-term) - Protein Information | |
| Name ACAT1 | |
| Synonyms ACAT, MAT | |
| Function Plays a major role in ketone body metabolism. | |
| Cellular Location Mitochondrion. | |
ACAT1 Antibody (N-term) - Related products
AP11099a: ACAT1 Antibody (N-term)
AP7560b: ACAT1 Antibody (C-term)
RI10047: ACAT1 predesign siRNA
DC03038: Human ACAT1 cDNA Clone
ACAT1 Antibody (N-term) - Application data
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ACAT1 Antibody (N-term) (Cat. #AP11099a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ACAT1 antibody detected the ACAT1 protein (arrow).
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ACAT1 Antibody (N-term) (Cat. #AP11099a)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACAT1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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ACAT1 Antibody (N-term) (Cat. #AP11099a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ACAT1 Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
REFERENCES
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Sakashita, N., et al. J. Lipid Res. 51(6):1263-1272(2010) Reynolds, C.A., et al. Hum. Mol. Genet. 19(10):2068-2078(2010) Fukao, T., et al. Mol. Genet. Metab. 100(1):37-41(2010) Thummler, S., et al. Tohoku J. Exp. Med. 220(1):27-31(2010)
