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ELMO2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ELMO2 Antibody (Center) AP11106c
    ELMO2 Antibody (Center) (Cat. #AP11106c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ELMO2 antibody detected the ELMO2 protein (arrow).
  • IHC-P - ELMO2 Antibody (Center) AP11106c
    ELMO2 Antibody (Center) (Cat. #AP11106c)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ELMO2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - ELMO2 Antibody (Center) AP11106c
    ELMO2 Antibody (Center) (Cat. #AP11106c) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96JJ3
Other Accession Q8BHL5, A4FUD6, NP_877496.1, NP_573403.1
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 82615 Da
Antigen Region 323-350 aa
Additional Information
Gene ID 63916
Other Names Engulfment and cell motility protein 2, Protein ced-12 homolog A, hCed-12A, ELMO2, CED12A, KIAA1834
Target/Specificity This ELMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-350 amino acids from the Central region of human ELMO2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsELMO2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELMO2
Synonyms CED12A, KIAA1834
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Cellular Location Cytoplasm. Cytoplasm, cytosol. Membrane
Tissue Location Widely expressed, with a higher expression in skeletal muscle, kidney and placenta
Research Areas
Citations (0)

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The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants encoding the same protein.


Bento, J.L., et al. Genomics 92(4):226-234(2008)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)
Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)
Castelo, R., et al. Nucleic Acids Res. 33(6):1935-1939(2005)

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Cat# AP11106c
(40 western blots)
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