|Application ||FC, WB, E|
|Calculated MW||50229 Da|
|Antigen Region||338-367 aa|
|Other Names||Fibroleukin, Fibrinogen-like protein 2, pT49, FGL2|
|Target/Specificity||This FGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-367 amino acids from the C-terminal region of human FGL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FGL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in physiologic lymphocyte functions at mucosal sites.|
|Tissue Location||Constitutively expressed in cytotoxic T-cells.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
Liu, Y., et al. Biochem. Biophys. Res. Commun. 396(2):555-561(2010)
Hsieh, Y.H., et al. Bull. Math. Biol. 72(1):122-132(2010)
Siu, K.L., et al. J. Gen. Virol. 90 (PT 9), 2107-2113 (2009) :
Han, M., et al. J. Biol. Chem. 283(47):32715-32729(2008)
Su, K., et al. World J. Gastroenterol. 14(39):5980-5989(2008)
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