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SFRS17A Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SFRS17A Antibody (Center) AP11133c
    SFRS17A Antibody (Center) (Cat. #AP11133c) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the SFRS17A antibody detected the SFRS17A protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q02040
Other Accession NP_005079.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 80735 Da
Antigen Region 307-336 aa
Additional Information
Gene ID 8227
Other Names A-kinase anchor protein 17A, AKAP-17A, 721P, B-lymphocyte antigen, Protein XE7, Protein kinase A-anchoring protein 17A, PRKA17A, Splicing factor, arginine/serine-rich 17A, AKAP17A, CXYorf3, DXYS155E, SFRS17A, XE7
Target/Specificity This SFRS17A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the Central region of human SFRS17A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSFRS17A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKAP17A
Synonyms CXYorf3, DXYS155E, SFRS17A, XE7
Function Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
Cellular Location Nucleus speckle
Tissue Location Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B- cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells.
Research Areas
Citations (0)
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Background

This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.

References

Jarnaess, E., et al. J. Biol. Chem. 284(50):35154-35164(2009)
Mangs, A.H., et al. Nucleic Acids Res. 34(17):4976-4986(2006)
Ried, K., et al. Hum. Mol. Genet. 7(11):1771-1778(1998)
Ellison, J.W., et al. Hum. Mol. Genet. 1(9):691-696(1992)
Voland, J.R., et al. Proc. Natl. Acad. Sci. U.S.A. 89(21):10425-10429(1992)

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$ 182.50
$ 70.00
Cat# AP11133c
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