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CUZD1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q86UP6 |
| Other Accession | NP_071317.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 68153 Da |
| Antigen Region | 579-607 aa |
| Gene ID | 50624 |
|---|---|
| Other Names | CUB and zona pellucida-like domain-containing protein 1, CUB and ZP domain-containing protein 1, Transmembrane protein UO-44, CUZD1 {ECO:0000312|EMBL:CAH700061} |
| Target/Specificity | This CUZD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 579-607 amino acids from the C-terminal region of human CUZD1. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CUZD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CUZD1 {ECO:0000312|EMBL:CAH70006.1} |
|---|---|
| Function | Localized to zymogen granules, where it functions in trypsinogen activation (By similarity). May indirectly regulate cell motility, cell-cell and cell/extracellular matrix interactions (PubMed:15184879). |
| Cellular Location | Zymogen granule membrane {ECO:0000250|UniProtKB:P70412}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P70412} |
| Tissue Location | Detected in pancreas and epithelium of ovary. Expressed at higher levels in ovarian tumors than in normal tissue |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.
References
Leong, C.T., et al. Oncogene 26(6):870-880(2007) Blanchetot, C., et al. Methods 35(1):44-53(2005) Leong, C.T., et al. Oncogene 23(33):5707-5718(2004) Deloukas, P., et al. Nature 429(6990):375-381(2004) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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