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HBO1/MYST2 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - HBO1/MYST2 Antibody (N-term) AP1113a
    HBO1/MYST2 Antibody (N-term) (Cat. #AP1113a) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HBO1/MYST2 antibody detected the HBO1/MYST2 protein (arrow).
  • IHC-P - HBO1/MYST2 Antibody (N-term) AP1113a
    Formalin-fixed and paraffin-embedded human testis tissue reacted with HBO1/MYST2 antibody (N-term) (Cat.#AP1113a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95251
Other Accession Q810T5, Q5SVQ0
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70642 Da
Antigen Region 99-130 aa
Additional Information
Gene ID 11143
Other Names Histone acetyltransferase KAT7, Histone acetyltransferase binding to ORC1, Lysine acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, MYST-2, KAT7, HBO1, HBOa, MYST2
Target/Specificity This HBO1/MYST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human HBO1/MYST2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHBO1/MYST2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KAT7
Synonyms HBO1, HBOa, MYST2
Function Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.
Cellular Location Nucleus, nucleoplasm
Tissue Location Ubiquitously expressed, with highest levels in testis.
Research Areas
Citations (0)

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HBO1/MYST2 is a histone acetyltransferase which specifically represses AR-mediated transcription. It may play a role in DNA replication.


Wu,Z.Q., Proc. Natl. Acad. Sci. U.S.A. 105 (6), 1919-1924 (2008)
Iizuka,M., Mol. Cell. Biol. 28 (1), 140-153 (2008)

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$ 295.00
$ 99.00
Cat# AP1113a
(40 western blots)
Availability: In Stock
Bulk Size
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