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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   THEMIS Antibody (C-term)   

THEMIS Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - THEMIS Antibody (C-term) AP11184b
    THEMIS Antibody (C-term) (Cat. #AP11184b) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the THEMIS antibody detected the THEMIS protein (arrow).
  • IHC-P - THEMIS Antibody (C-term) AP11184b
    THEMIS Antibody (C-term) (Cat. #AP11184b)immunohistochemistry analysis in formalin fixed and paraffin embedded human thymoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of THEMIS Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N1K5
Other Accession NP_001010923.1, NP_001158157.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 73452 Da
Antigen Region 559-588 aa
Additional Information
Gene ID 387357
Other Names Protein THEMIS, Thymocyte-expressed molecule involved in selection, THEMIS, C6orf190, C6orf207
Target/Specificity This THEMIS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-588 amino acids from the C-terminal region of human THEMIS.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTHEMIS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C6orf190, C6orf207
Function Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity).
Cellular Location Cytoplasm. Nucleus
Research Areas
Citations (0)

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This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Bhatti, P., et al. Radiat. Res. 173(2):214-224(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Patrick, M.S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(38):16345-16350(2009)

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$ 295.00
$ 99.00
Cat# AP11184b
(40 western blots)
Availability: In Stock
Bulk Size
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