|Application ||WB, E|
|Other Accession||A6QNZ8, NP_110423.3|
|Calculated MW||19224 Da|
|Antigen Region||65-95 aa|
|Other Names||Vesicular, overexpressed in cancer, prosurvival protein 1, EGFR-coamplified and overexpressed protein, ECop, Glioblastoma-amplified secreted protein, Putative NF-kappa-B-activating protein 055N, VOPP1, ECOP, GASP|
|Target/Specificity||This ECOP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-95 amino acids from the Central region of human ECOP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ECOP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.|
|Cellular Location||Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=When overexpressed, localizes in the nucleus and perinuclear regions|
|Tissue Location||Widely expressed with highest levels in thymus and ovary.|
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Provided below are standard protocols that you may find useful for product applications.
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Baras, A., et al. Oncogene 28(32):2919-2924(2009)
Chechlinska, M., et al. BMC Genomics 10, 261 (2009) :
Brem, H., et al. Mol. Med. 13 (1-2), 30-39 (2007) :
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