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TIEG Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TIEG Antibody (Center) AP11203c
    Western blot analysis of TIEG (arrow) using rabbit polyclonal TIEG Antibody (Center) (Cat. #AP11203c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TIEG gene.
  • FC - TIEG Antibody (Center) AP11203c
    TIEG Antibody (Center) (Cat. #AP11203c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13118
Other Accession NP_005646
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52555 Da
Antigen Region 198-225 aa
Additional Information
Gene ID 7071
Other Names Krueppel-like factor 10, EGR-alpha, Transforming growth factor-beta-inducible early growth response protein 1, TGFB-inducible early growth response protein 1, TIEG-1, KLF10, TIEG, TIEG1
Target/Specificity This TIEG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-225 amino acids from the Central region of human TIEG.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTIEG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLF10
Synonyms TIEG, TIEG1
Function Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.
Cellular Location Nucleus {ECO:0000250|UniProtKB:O89091}.
Research Areas
Citations (0)

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Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.


Kim, J., et al. Biochem. Biophys. Res. Commun. 401(3):412-416(2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Subramaniam, M., et al. Biofactors 36(1):8-18(2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)

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$ 295.00
$ 99.00
Cat# AP11203c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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