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LARS Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • FC - LARS Antibody (N-term) AP11207a
    LARS Antibody (N-term) (Cat. #AP11207a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - LARS Antibody (N-term) AP11207a
    LARS Antibody (N-term) (Cat. #AP11207a) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the LARS antibody detected the LARS protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P2J5
Other Accession NP_064502
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 134466 Da
Antigen Region 176-205 aa
Additional Information
Gene ID 51520
Other Names Leucine--tRNA ligase, cytoplasmic, Leucyl-tRNA synthetase, LeuRS, LARS, KIAA1352
Target/Specificity This LARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-205 amino acids from the N-terminal region of human LARS.
Dilution FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLARS Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1352
Function Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.
Cellular Location Cytoplasm.
Citations (0)

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This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. Alternatively spliced transcript variants of this gene have been found; however, their full-length nature is not known.


Pang, Y.L., et al. Biochemistry 48(38):8958-8964(2009)
Seiradake, E., et al. J. Mol. Biol. 390(2):196-207(2009)
Shin, S.H., et al. Exp. Mol. Med. 40(2):229-236(2008)
Maeso, E., et al. Neuromuscul. Disord. 17(5):415-418(2007)
Lue, S.W., et al. Biochemistry 46(15):4466-4472(2007)

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$ 295.00
$ 99.00
Cat# AP11207a
(40 western blots)
Availability: In Stock
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