|Application ||WB, E|
|Other Accession||Q99MR1, NP_072096.2|
|Calculated MW||114601 Da|
|Antigen Region||666-694 aa|
|Other Names||PERQ amino acid-rich with GYF domain-containing protein 1, GRB10-interacting GYF protein 1, GIGYF1, CDS2, PERQ1|
|Target/Specificity||This GIGYF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-694 amino acids from the Central region of human GIGYF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GIGYF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity).
Szafranski, K., et al. Genome Biol. 8 (8), R154 (2007) :
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Giovannone, B., et al. J. Biol. Chem. 278(34):31564-31573(2003)
Wilson, M.D., et al. Nucleic Acids Res. 29(6):1352-1365(2001)
Glockner, G., et al. Genome Res. 8(10):1060-1073(1998)
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