|Application ||WB, IHC-P, FC, E|
|Calculated MW||38812 Da|
|Antigen Region||303-335 aa|
|Other Names||2-acylglycerol O-acyltransferase 1, Acyl-CoA:monoacylglycerol acyltransferase 1, MGAT1, Diacylglycerol O-acyltransferase candidate 2, hDC2, Diacylglycerol acyltransferase 2-like protein 1, Monoacylglycerol O-acyltransferase 1, MOGAT1, DC2, DGAT2L1|
|Target/Specificity||This MOGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-335 amino acids from the C-terminal region of human MOGT1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MOGT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 220.127.116.11) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM].
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Winter, A., et al. Cytogenet. Genome Res. 102 (1-4), 42-47 (2003) :
Yen, C.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(13):8512-8517(2002)
Cases, S., et al. J. Biol. Chem. 276(42):38870-38876(2001)
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