|Application ||WB, IHC-P, E|
|Calculated MW||113557 Da|
|Antigen Region||298-328 aa|
|Other Names||Tolloid-like protein 2, 3424-, TLL2, KIAA0932|
|Target/Specificity||This TLL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-328 amino acids from the Central region of human TLL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TLL2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin.
Mac Sweeney, A., et al. J. Mol. Biol. 384(1):228-239(2008)
Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Uzel, M.I., et al. J. Biol. Chem. 276(25):22537-22543(2001)
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