|Application ||WB, IHC-P, FC, E|
|Other Accession||Q9D4P0, NP_848930.1|
|Calculated MW||20375 Da|
|Antigen Region||122-154 aa|
|Other Names||ADP-ribosylation factor-like protein 5B, ADP-ribosylation factor-like protein 8, ARL5B, ARL8|
|Target/Specificity||This ARL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-154 amino acids from the C-terminal region of human ARL8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARL8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds and exchanges GTP and GDP.|
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Provided below are standard protocols that you may find useful for product applications.
ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Sebald, E., et al. Gene 311, 147-151 (2003) :
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