|Application ||WB, E|
|Other Accession||NP_001111.3, NP_001139541.1|
|Calculated MW||48339 Da|
|Antigen Region||245-274 aa|
|Other Names||Major facilitator superfamily domain-containing protein 10, Tetracycline transporter-like protein, MFSD10, TETRAN|
|Target/Specificity||This MFS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the Central region of human MFS10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MFS10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein likely functions in efflux of organic anions, including the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Alternatively spliced transcript variants have been described. [provided by RefSeq].
Ushijima, H., et al. Biochem. Biophys. Res. Commun. 374(2):325-330(2008)
Mima, S., et al. FEBS Lett. 581(7):1457-1463(2007)
Duyao, M.P., et al. Hum. Mol. Genet. 2(6):673-676(1993)
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