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A2LD1 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # Size Availability Price  
AP11357b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP11357b-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
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A2LD1 Antibody (C-term) - Product info

ApplicationWB, IHC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ9BVM4
Other AccessionQ4KM86, Q923B0, NP_001182016.1, NP_149101.1
ReactivityMouse
PredictedRat
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW17329 Da

A2LD1 Antibody (C-term) - Additional info

Gene ID 87769
Other Names
A2LD1; Gamma-glutamylaminecyclotransferase; AIG2-like domain-containing protein 1
Target/Specificity
This A2LD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-161 amino acids from the C-terminal region of human A2LD1.
Dilution
WB~~1:100~500
IHC~~1:50~100
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
A2LD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

A2LD1 Antibody (C-term) - Protein Information

Name GGACT
Synonyms A2LD1
Function
Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross- linked by transglutaminases. Catalyzes the formation of 5- oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma- glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine

A2LD1 Antibody (C-term) - Related products

AP11357b: A2LD1 Antibody (C-term)

DC00501: Human A2LD1 cDNA Clone

A2LD1 Antibody (C-term) - Application data

  • A2LD1 Antibody (C-term) (Cat. #AP11357b) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the A2LD1 antibody detected the A2LD1 protein (arrow).

  • A2LD1 Antibody (C-term) (Cat. #AP11357b)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of A2LD1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

A2LD1 Antibody (C-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.

REFERENCES

Oakley, A.J., et al. J. Biol. Chem. 285(13):9642-9648(2010)