PTCHD1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q96NR3 |
Other Accession | Q14B62, NP_775766.2 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 101341 Da |
Antigen Region | 611-639 aa |
Gene ID | 139411 |
---|---|
Other Names | Patched domain-containing protein 1, PTCHD1 |
Target/Specificity | This PTCHD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-639 amino acids from the Central region of human PTCHD1. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PTCHD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PTCHD1 (HGNC:26392) |
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Function | Required for the development and function of the thalamic reticular nucleus (TRN), a part of the thalamus that is critical for thalamocortical transmission, generation of sleep rhythms, sensorimotor processing and attention. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed, including in various regions of the brain with highest expression in the gray and white cerebellum, followed by the cerebellar vermis and the pituitary gland |
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Provided below are standard protocols that you may find useful for product applications.
References
Pinto, D., et al. Nature (2010) In press :
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